All functions

Milo()

The Milo constructor

annotateNhoods()

Add annotations from colData to DA testing results

buildFromAdjacency

Build a graph from an input adjacency matrix

buildGraph()

Build a k-nearest neighbour graph

buildNhoodGraph()

Build an abstracted graph of neighbourhoods for visualization

calcNhoodDistance()

Calculate within neighbourhood distances

calcNhoodExpression()

Average expression within neighbourhoods

countCells()

Count cells in neighbourhoods

findNhoodMarkers

Identify post-hoc neighbourhood marker genes

graphSpatialFDR

Control the spatial FDR

makeNhoods()

Define neighbourhoods on a graph (fast)

matrixORMatrix-class

The Milo container class

Milo-methods

Get and set methods for Milo objects

plotDAbeeswarm()

Visualize DA results as a beeswarm plot

plotNhoodExpressionDA()

Visualize gene expression in neighbourhoods

plotNhoodGraph()

Plot graph of neighbourhood

plotNhoodGraphDA()

Plot Milo results on graph of neighbourhood

plotNhoodSizeHist()

Plot histogram of neighbourhood sizes

sim_discrete

sim_discrete

sim_trajectory

Simulated linear trajectory data

testDiffExp

Perform post-hoc differential gene expression analysis

testNhoods

Perform differential neighbourhood abundance testing